Compositions and method for improving wound healing

Details Compositions and method for improving wound healing Compositions and method for improving wound healing

A - Human Necessities

61

K

167/103.9

A61K 38/39 (2006.01)

Patent

CA 1258630

- 30 - Abstract of Disclosure The healing of wounds is promoted by con- tacting the wound surfaces with a suspension of collagen and a glycosaminoglycan that is chemotactic for fibroblasts and/or endothelial cells. Typical glycosaminoglycans that exhibit the desired chemotaxis are heparin, heparan sulfate, and alginate. Two or more glycosaminoglycans can be present in the suspen- sions. Collagen is present in the suspension in the order of 7-10 mg/ml; while the glycosaminoglycan is present in much lower concentrations, e.g, 250-350 µg/ml. Application of the collagen/glycosaminoglycan suspension to open wounds greatly increases the rate of healing.

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