A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/45 (2006.01) A61K 35/12 (2006.01) A61K 35/44 (2006.01) A61K 48/00 (2006.01) A61P 9/00 (2006.01) C12N 5/10 (2006.01) C12N 15/00 (2006.01) C12N 15/85 (2006.01) C12Q 1/48 (2006.01) C12N 9/12 (2006.01) C12N 15/54 (2006.01)
Patent
CA 2705862
The invention provides compositions (e.g., pharmaceutical compositions) comprising nucleic acids encoding the serine/threonine kinase PIM-I, and methods for making and using them; including methods for inducing cellular proliferation, and protecting cardiac cells from hypoxia and cellular apoptosis. The invention provides compositions (e.g., pharmaceutical compositions) comprising nucleic acids encoding PIM-I, and methods for enhancing the regenerative potential of stem cells in the heart.
L'invention concerne des compositions (par exemple, des compositions pharmaceutiques) comprenant des acides nucléiques codant la sérine/thréonine kinase PIM-I, et des procédés pour les préparer et les utiliser, notamment des procédés pour induire la prolifération cellulaire et protéger les cellules cardiaques de l'hypoxie et de l'apoptose cellulaire. L'invention concerne des compositions (par exemple, des compositions pharmaceutiques) comprenant des acides nucléiques codant PIM-I, et des procédés pour augmenter le potentiel de régénération des cellules souches dans le c ur.
Muraski John A. Jr.
Sussman Mark A.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
San Diego State University Research Foundation
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