Compositions and method for reducing scar formation in wound...

A - Human Necessities – 61 – K

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A61K 38/17 (2006.01) A61P 9/00 (2006.01) A61P 17/02 (2006.01)

Patent

CA 2720280

The invention pertains to a method of reducing scar formation during wound healing by administering a phos-phatidylserine -binding compound, in particular an annexin, to a subject in need thereof. The healing wound may be a skin dam-age, but it may also be a myocardium e.g. which is at risk of suffering or is recovering from a heart failure.

L'invention porte sur un procédé de réduction de la formation d'une cicatrice durant la cicatrisation d'une plaie par l'administration à un sujet en ayant besoin d'un composé de liaison à la phosphatidylsérine, en particulier une annexine. La plaie cicatrisant peut être un dommage cutané, mais ce peut également être un myocarde, par exemple, qui est à risque de souffrir ou qui récupère d'une insuffisance cardiaque.

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