A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/19 (2006.01) A61K 39/39 (2006.01) A61K 39/395 (2006.01) C07K 14/535 (2006.01) C07K 14/54 (2006.01) C07K 16/24 (2006.01) C07K 16/42 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2176115
The invention describes compositions comprising adding granulocyte-macrophage colony stimulating factor (GM-CSF), interleukin-3 (IL-3), or a combination thereof useful for stimulating the release of antibody by B cells. Methods of using the compositions, pharmaceutical compositions, vaccines, and vaccines adjuvants are also described. In addition, this invention describes an assay system useful for identifying compounds capable of stimulating the release of antibody by B cells.
L'invention concerne des compositions comprenant le facteur stimulant la prolifération des granulocytes et des macrophages (GMSF), de l'interleukine-3 (IL-3), ou une combinaison de ces derniers utile pour stimuler la libération d'anticorps par les lymphocytes B. L'invention porte également sur des procédés d'utilisation de ces compositions, des compositions pharmaceutiques, des vaccins et des adjuvants de vaccins. Elle se rapporte également à un système d'analyse utile pour identifier des composés capables de stimuler la libération d'anticorps par les lymphocytes B.
Mond James J.
Snapper Clifford M.
Henry M. Jackson Foundation
Kirby Eades Gale Baker
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