Compositions and method for tissue preservation

A - Human Necessities – 01 – N

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A01N 1/02 (2006.01)

Patent

CA 2678486

Methods and compositions for resuscitating, storing, and preserving functional integrity of organs and tissues. Metabolic function is maintained by sustaining ATP levels, mitochondrial function, cardiomyocyte contractility, prevention of acidosis, inhibition of induction of apoptosis, maintaining ionontrophy and lusiotrophy by regulating calcium, sodium, potassium and chloride ions.

Cette invention se rapporte à des procédés et à des compositions permettant de restaurer, de stocker et de conserver l'intégrité fonctionnelle d'organes et de tissus. La fonction métabolique est maintenue en conservant les taux d'ATP, la fonction mitochondriale, la fonction contractile des cardiomyocytes, en luttant contre l'acidose, en inhibant l'induction de l'apoptose, en maintenant l'inotropie et la lusitropie par régulation des ions calcium, sodium, potassium et chlorure.

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