Compositions and methods comprising control nucleic acid

C - Chemistry – Metallurgy – 12 – Q

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Details

C12Q 1/68 (2006.01) C07H 21/04 (2006.01) C12P 19/34 (2006.01)

Patent

CA 2457427

The present invention relates, in part, to control nucleic acid molecules having no significant sequence homology to any known nucleic acid, and predefined G/C-content. The present invention further relates to method of using control nucleic acid molecules to validate microarray analyses, compositions comprising control nucleic acid molecules, and kits comprising control nucleic acid molecules.

L'invention concerne en partie des molécules d'acide nucléique témoin ne présentant aucune homologie de séquence significative avec un acide nucléique connu, et à teneur prédéfinie en G/C. L'invention a en outre trait à un procédé d'utilisation des molécules d'acide nucléique témoin pour valider des analyses de microréseaux, à des compositions contenant des molécules d'acide nucléique témoin et à des trousses contenant de telles molécules.

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