C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 261/18 (2006.01) C07D 235/30 (2006.01) C07D 403/02 (2006.01)
Patent
CA 2576971
Compositions and methods comprising proteinase activated receptor antagonists are provided. More particularly, the present invention relates to the use of proteins, peptides and molecules that bind to proteinase activated receptor 2, and inhibit the processes associated with the activation of that receptor. More specifically, the present invention provides novel compositions and methods for the treatment of disorders and diseases such as those associated with abnormal cellular proliferation, angiogenesis, inflammation and cancer.
La présente invention a trait à des compositions et des procédés comportant des antagonistes de récepteur activé par la protéinase. Plus particulièrement, la présente invention a trait à l'utilisation de protéines, de peptides et de molécules de liaison au récepteur 2 activé par la protéinase, et sont inhibiteurs de processus associés à l'activation de ce récepteur. De manière plus spécifique, la présente invention a trait à de nouvelles compositions et de nouveaux procédés pour le traitement de troubles et de maladies tels que ceux/celles associé(e)s à une prolifération cellulaire anormale, l'angiogenèse, l'inflammation et le cancer.
Agoston Gregory E.
Hembrough Todd A.
Lavallee Theresa M.
Shah Jamshed H.
Suwandi Lita
Entremed Inc.
Finlayson & Singlehurst
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