Compositions and methods comprising serine protease variants

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 9/54 (2006.01) C11D 3/386 (2006.01) C11D 7/42 (2006.01) C12N 15/57 (2006.01)

Patent

CA 2743047

The present invention provides methods for protein engineering and serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.

La présente invention concerne des méthodes de conception de protéines et des variantes de protéase à sérine obtenues à partir desdites méthodes. De façon spécifique, la présente invention concerne des variantes de protéase à sérine comportant une ou plusieurs substitutions par rapport à une protéase à sérine de référence. De plus, la présente invention concerne des compositions incluant ces variantes de protéase à sérine. Dans certains modes de réalisation, la présente invention concerne des compositions nettoyantes comportant au moins l'une de ces variantes de protéase à sérine.

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