Compositions and methods comprising variant microbial proteases

Details Compositions and methods comprising variant microbial proteases Compositions and methods comprising variant microbial proteases

C - Chemistry, Metallurgy

12

N

C12N 9/54 (2006.01) A23K 1/165 (2006.01)

Patent

CA 2726370

The present invention provides methods for protein engineering. Specifically, the invention provides methods utilizing site evaluation libraries to design libraries that optimize two or more properties of a protein. The present invention also provides variant subtilisins suitable for various uses.

La présente invention porte sur des procédés pour la synthèse par génie génétique des protéines. De façon spécifique, l'invention porte sur des procédés utilisant des bibliothèques d'évaluation de sites pour concevoir des bibliothèques qui permettent d'optimiser deux propriétés ou plus d'une protéine. La présente invention porte également sur des subtilisines variantes appropriées pour diverses utilisations.

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