Compositions and methods comprising west nile virus...

Details Compositions and methods comprising west nile virus... Compositions and methods comprising west nile virus...

A - Human Necessities

61

K

A61K 39/12 (2006.01) C07K 14/18 (2006.01)

Patent

CA 2440593

This application is directed to compositions and methods comprising isolated and purified West Nile virus polypeptides and immunogenic fragments thereof, nucleic acid molecules encoding them and antibodies specific for such polypeptides or fragments. Such polypeptides and fragments, fusion proteins comprising them and antibodies are useful as vaccines to treat, inhibit or prevent West Nile virus infection or disease, to detect West Nile virus infection and to monitor the course of disease or immunization.

Cette invention concerne des procédés et des compositions comprenant des polypeptides isolés et purifiés du virus West Nile et des fragments immunogènes de ceux-ci, des molécules d'acide nucléique les codant et des anticorps spécifiques de ces polypeptides ou fragments. Ces polypeptides et fragments, les protéines de fusion les comprenant et les anticorps sont utiles comme vaccins pour traiter, inhiber ou prévenir l'infection ou la maladie imputable au virus West Nile, pour détecter cette infection et surveiller la progression de la maladie ou de l'immunisation.

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