Compositions and methods employing alternative reading frame...

C - Chemistry – Metallurgy – 12 – N

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C12N 9/90 (2006.01) A61K 38/17 (2006.01) A61K 38/45 (2006.01) A61K 38/51 (2006.01) A61K 38/52 (2006.01) A61K 39/00 (2006.01) A61P 35/00 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 14/82 (2006.01) C07K 19/00 (2006.01) C12N 9/12 (2006.01) C12N 9/16 (2006.01) C12N 9/88 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2514288

Provided are alternative reading frame (ARF) polypeptides as well as antigen presenting cell (APC) and dendritic cell (DC) based compositions and methods that employ alternative reading frame polypeptides. ARF polypeptides and ARF polypeptide-based compositions and methods are useful in the treatment of cancer and infectious disease.

L'invention concerne des polypeptides à cadre de lecture (ARF) différent ainsi qu'une cellule présentant un antigène (APC), des compositions à base de cellules dentritiques (DC) et des procédés utilisant des polypeptides a cadre de lecture différent. L'invention concerne des polypeptides ARF et des compositions à base de polypeptides ARF ainsi que des procédés utilisés dans le traitement du cancer et des maladies infectieuses.

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