Compositions and methods for achieving immune suppression

Details Compositions and methods for achieving immune suppression Compositions and methods for achieving immune suppression

A - Human Necessities

61

K

A61K 38/20 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61P 37/06 (2006.01) C07K 14/54 (2006.01) C07K 14/705 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2408691

Composition comprising a first agent that targets an interleukin-15 receptor (IL-15R) and a second agent that inhibits a costimulatory signal transmitted between a T cell and an antigen-presenting cell (APC). Said composition may be used for the diagnosis and therapy of immune duiseases, especially autoimmune diseases.

L'invention porte sur une composition comprenant un premier agent ciblant un récepteur de l'interleukine 15 et un second agent inhibant un signal costimulateur transmis entre un lymphocyte T et une cellule présentant un antigène. Cette composition peut être utilisée dans le diagnostic et le traitement des maladies immunes, notamment les maladies auto-immunes.

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