Compositions and methods for activating genes of interest

Details Compositions and methods for activating genes of interest Compositions and methods for activating genes of interest

C - Chemistry, Metallurgy

07

H

C07H 21/02 (2006.01) C12N 5/10 (2006.01) C12N 15/11 (2006.01) C12N 15/63 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2293833

Compositions and methods for activating genes of interest are provided. The compositions comprise a masked targeted expression cassette which expresses a gene product only in the presence of a target molecule. The cassettes are useful for the treatment of disease and for preventing the proliferation of neoplastic cells.

Cette invention concerne des compositions et procédés destinés à activer des gènes donnés. Ces compositions comportent une cassette d'expression ciblée masquée qui exprime un produit génique seulement en présence d'une molécule cible. Ces cassettes sont utilisées pour traiter des maladies et pour empêcher la prolifération de cellules néoplasiques.

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