Compositions and methods for adipose abundant protein

Details Compositions and methods for adipose abundant protein Compositions and methods for adipose abundant protein

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 31/7088 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 3/00 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2447209

Is isolated polypeptide comprising an amino acid sequence having at least 80% sequence identity to the sequence SEQ ID NOS:4 or 6, polynucleotides encoding these peptides, and antibodies to the polypeptides are useful in treating metabolic disorders or disorders associated with changes in adipose tissue physiological function or mass.

L'invention concerne un polypeptide isolé comprenant une séquence d'acide aminé dont l'identité de séquence est d'au moins 80 % par rapport à l'identité de séquence SEQ ID NOS:4 ou 6, des polynucléotides codant ces peptides, et des anticorps contre lesdits polypeptides, utiles dans le traitement de troubles du métabolisme, ou de troubles associés à des modifications au niveau de la masse ou de la fonction physiologique du tissu adipeux.

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