Compositions and methods for alleviating hyposalivation and...

Details Compositions and methods for alleviating hyposalivation and... Compositions and methods for alleviating hyposalivation and...

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 31/353 (2006.01) A61K 36/752 (2006.01) A61K 36/87 (2006.01)

Patent

CA 2743615

Various compositions and methods are provided to allevi-ate one or more symptoms associated with hyposalivation or xerostomia. Preferred compositions and methods employ one or more plant extracts and/or a proanthocyanidin at a concentration effective to reduce or elimi-nate the symptoms. Especially preferred extracts are isolated from a fruit and/or seed (e.g., grape, cranberry, blue berry, black berry, etc.), and where a second extract is present, such extract is preferably isolated from a citrus fruit (e.g., lemon, orange, lime, grapefruit, tangerine, mandarin or-ange, ugli fruit, etc.).

La présente invention concerne diverses compositions et méthodes destinées au soulagement d'un ou de plusieurs des symptômes associés à lhyposalivation ou à la xérostomie. Les compositions et méthodes préférées emploient un ou plusieurs extraits végétaux et/ou une proanthocyanidine à concentration suffisante pour réduire ou éliminer les symptômes. Les extraits spécialement préférés sont isolés à partir d'un fruit et/ou d'une graine (par exemple raisin, canneberge, myrtille, mûre, etc.) et, lorsqu'un second extrait est présent, un tel extrait est préférentiellement isolé à partir dun agrume (par exemple citron, orange, lime, pamplemousse, murcotte, mandarine, ugli, etc.)

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