Compositions and methods for biocatalytic engineering

Details Compositions and methods for biocatalytic engineering Compositions and methods for biocatalytic engineering

C - Chemistry, Metallurgy

12

N

C12N 1/00 (2006.01)

Patent

CA 2615057

Provided herein are compositions and methods for metabolic pathway engineering. The methods involve combining two or more cells expressing potential pathway proteins extracellularly in the presence of reactants. Also provided are librarie of cells expressing a plurality of pathway components and/or a plurality of variants of a given pathway component extracellularly.

La présente invention concerne des compositions et des procédés destinés à l'ingénierie des voies métaboliques. Le procédé consiste à combiner plusieurs cellules exprimant extracellulairement les protéines potentielles de la voie en présence de réactifs. L'invention concerne également une échantillothèque de cellules exprimant extracellulairement une pluralité de composants de la voie et/ou une pluralité de variantes d'un composant donné de la voie.

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