Compositions and methods for biological sample storage

Details Compositions and methods for biological sample storage Compositions and methods for biological sample storage

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07D 207/04 (2006.01) C07D 239/02 (2006.01) C12N 11/02 (2006.01)

Patent

CA 2761675

Compositions and methods are disclosed for substantially dry storage at ambient or elevated temperatures of biological samples such as nucleic acids,, proteins and cells in a form from which the samples can be substantially recovered, using a dissolvable or dissociable dry storage matrix comprising a borate composition and a stabilizer as disclosed, such as any of a number of zwitterionic stabilizers.

La présente invention concerne des compositions et des procédés permettant un stockage essentiellement à l'état déshydraté et à température ambiante ou plus élevée d'échantillons biologiques constitués, par exemple, d'acides nucléiques, de protéines et de cellules, ledit stockage se faisant sous une forme permettant une bonne récupération des échantillons et faisant appel à une matrice de stockage déshydratée soluble ou dissociable comprenant une composition de borate et un stabilisant tel que décrit ici, par exemple l'un quelconque d'un certain nombre de stabilisants zwitterioniques.

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