Compositions and methods for cancer diagnostics comprising...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2615858

The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, so-called ,,pan cancer markers". In particular, the present invention provides methods of identifying methylation patterns in genes associated with specific cancers, and their related uses. In another aspect, the present invention provides methods of selecting and combining useful sets of pan cancer markers.

L'invention concerne des compositions et des méthodes de diagnostic du cancer, notamment, mais non exclusivement, des marqueurs dits "pantumoraux" (non spécifiques d'un seul type de cancer). L'invention concerne en particulier des procédés permettant d'identifier les profils de méthylation des gènes associés à des cancers spécifiques, ainsi que leurs utilisations connexes. Dans un aspect différent, l'invention concerne des méthodes permettant de sélectionner et de combiner des ensembles utiles de marqueurs pantumoraux.

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