Compositions and methods for catalyzing hydrolysis of hiv gp120

Details Compositions and methods for catalyzing hydrolysis of hiv gp120 Compositions and methods for catalyzing hydrolysis of hiv gp120

C - Chemistry, Metallurgy

07

K

C07K 16/10 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C12N 9/00 (2006.01) C12P 21/08 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2223914

A catalytic antibody and components thereof which cleave HIV gp120 are disclosed. Methods of isolating, cloning and purifying such antibodies or antibody components from patients are also described. The compositions described may provide utility in the treatment of HIV infection.

L'invention porte sur un anticorps catalytique et ses composants, provenant de patients, qui scindent la gp120 du VIH, et sur leurs procédés d'isolement, de clonage et de purification. Ces compositions peuvent s'avérer utiles pour le traitement des infections dues au VIH.

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