A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/56 (2006.01) A61K 31/565 (2006.01) A61K 31/57 (2006.01) A61K 31/58 (2006.01)
Patent
CA 2205897
Compositions and methods for use in preventing conception or treating benign gynecological disorders, wherein an effective amount of an antiprogestational agent [e.g., progesterone (progestin, progestogen, gestagen) antagonist or progesterone synthesis inhibitor] administered over a first period of time is combined with an effective amount of a progestogen for a second period of time. The antiprogestational agent is selected from single agents or mixture thereof. The progestogen is selected from single agents or mixtures of natural or synthetic progestogens. The formulations are effective as contraceptive agents and for treatment of benign gynecological disorders including uterine fibroids, premestrual syndrome, dysfunctional uterine bleeding, polycystic ovarian syndrome and endometriosis.
Compositions et méthodes de contraception et de traitement de troubles gynécologiques bénins recourant à un antiprogestatif [par exemple un antagoniste de la progestérone (progestine, progestogène, gestagène) ou un inhibiteur de la synthèse de la progestérone] administré pendant une première période combiné à un progestatif administré pendant une deuxième période. L'antiprogestatif peut consister en substances simples ou en leur mélange, et le progestatif en substances simples ou en mélanges de progestatifs naturels ou synthétiques. Ces compositions s'avèrent efficaces comme agents contraceptifs et pour le traitement de troubles gynécologiques bénins, dont les fibromes utérins, le syndrome prémenstruel, les hémorragies utérines dysfonctionnelles, la polykystose ovarienne et l'endométriose.
Daniels John R.
Pike Malcolm Cecil
Spicer Darcy V.
Balance Pharmaceuticals Inc.
Oyen Wiggs Green & Mutala Llp
LandOfFree
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