Compositions and methods for controlled release

Details Compositions and methods for controlled release Compositions and methods for controlled release

A - Human Necessities

61

K

A61K 47/48 (2006.01) A01N 37/18 (2006.01) A01N 43/04 (2006.01) A61K 9/00 (2006.01) A61K 31/7088 (2006.01) A61K 31/711 (2006.01) A61K 45/00 (2006.01) A61K 47/26 (2006.01) A61K 47/36 (2006.01) A61K 48/00 (2006.01) A61P 25/04 (2006.01) A61P 31/04 (2006.01) A61P 31/10 (2006.01) A61P 31/14 (2006.01) A61P 35/00 (2006.01) A61P 37/06 (2006.01) C07H 21/00 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C12Q 1/44 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2464131

Methods and compositions are provided for the controlled release of an active agent. The composition includes an oligonucleotide scaffold and a substantially complementary oligonucleotide factor. An active agent is attached to the oligonucleotide factor. The two oligonucleotides are differentially degradable, so that degradation of the scaffold occurs a faster rate than the degradation of the factor. As the scaffold degrades, the factor is released. The active agent can be a therapeutic agent, or a diagnostic agent.

L'invention a trait à des procédés et à des compositions permettant la libération contrôlée d'un agent actif. La composition contient un squelette oligonucléotidique et un facteur oligonucléotidique sensiblement complémentaire. Un agent actif est fixé au facteur oligonucléotidique. Les deux oligonucléotides sont dégradables de façon différentielle, de façon que la dégradation du squelette se fasse plus rapidement que celle du facteur. Lors de la dégradation du squelette, le facteur est libéré. L'agent actif peut être un agent thérapeutique ou un agent de diagnostic.

Affiliated with

Also associated with

Rating

Compositions and methods for controlled release does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions and methods for controlled release, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods for controlled release will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1631494