Compositions and methods for controlling tissue factor...

Details Compositions and methods for controlling tissue factor... Compositions and methods for controlling tissue factor...

A - Human Necessities

61

K

A61K 39/395 (2006.01)

Patent

CA 2628238

Compositions and methods for treating a disease dependent upon tissue factor/factor VIIa signaling in a mammalian subject is provided. The methods comprise administering an inhibitor of tissue factor signaling to the mammalian subject. The inhibitor is effective in reducing the incidence of disease in the mammalian subject. Also provided are methods of screening for modulators of tissue factor/factor VIIa signaling.

La présente invention concerne des compositions et des procédés destinés à traiter une maladie dépendant de la signalisation du facteur tissulaire/facteur VIIa chez un mammifère. Les procédés comprennent l~administration d~un inhibiteur de signalisation du facteur tissulaire chez le mammifère. L~inhibiteur est efficace pour réduire l~incidence de la maladie chez le mammifère. L~invention concerne également des procédés de criblage pour des modulateurs de signalisation du facteur tissulaire/facteur VIIa.

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