Compositions and methods for delivering antibacterial,...

A - Human Necessities – 61 – K

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A61K 9/06 (2006.01) A61K 9/00 (2006.01) G01N 33/50 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2463711

The ointments and methods of the invention treat oral and vaginal fungal and yeast infections. Ointments comprise antifungals and/or antibacterials, and a mixture of water-soluble, and water-insoluble components, which effectively treat oral and/or vaginal infections in a single dose or multiple doses comprise retaining antifungals and/or antibacterials for an effective time above a minimum concentration. Methods of treating the infections in a single dose comprise methods for determining whether ointments will be effective in a single dose test blood for concentration of antifungals and antibacterials at set time intervals.

L'invention concerne des onguents et des méthodes permettant de traiter des infections buccales et vaginales provoquées par des champignons et des levures. Ces onguents renferment des agents antifongiques et/ou antibactériens, et un mélange de composés hydro-solubles et hydro-insolubles, qui permettent de traiter efficacement des infections buccales et/ou vaginales, au moyen d'une dose unique ou de doses multiples par le biais de la retenue des agents antifongiques et/ou antibactériens, durant une période de temps efficace, au-dessus d'une concentration minimale. Cette invention a aussi pour objet des méthodes de traitement des infections au moyen d'une dose unique, notamment des méthodes permettant de déterminer, si des onguents seront efficaces dans un échantillon sanguin à dose unique en vue de concentrer les agents antifongiques et/ou antibactériens, à des intervalles de temps fixés.

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