Compositions and methods for delivery of glycopeptide...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 19/00 (2006.01) A61L 31/08 (2006.01) A61L 31/10 (2006.01) A61L 31/16 (2006.01) C07K 7/08 (2006.01) C07K 14/00 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2703482

The presently disclosed subject matter relates to peptides having binding affinity for glycopeptide antibiotics and methods and compositions for delivering glycopeptide antibiotic to the surface of medical devices. The peptide compositions can comprise a peptide having binding affinity for a surface material of a medical device that is coupled to the peptide having binding affinity for glycopeptide antibiotic. Also provided are methods of applying the peptide compositions to a medical device by contact-ing the peptide compositions with a surface of the medical device. In addition, kits are provided comprising the peptide compositions.

La présente invention concerne des peptides ayant une affinité de liaison pour des antibiotiques glycopeptidiques et des procédés et des compositions pour administrer un antibiotique glycopeptidique à la surface de dispositifs médicaux. Les compositions peptidiques peuvent comporter un peptide ayant une affinité de liaison pour un matériau de surface d'un dispositif médical qui est couplé au peptide ayant une affinité de liaison pour un antibiotique glycopeptidique. L'invention propose également des procédés d'application des compositions peptidiques sur un dispositif médical par la mise en contact des compositions peptidiques avec une surface du dispositif médical. De plus, l'invention propose des kits comportant les compositions peptidiques.

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