Compositions and methods for detecting cyclic analogs of...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/26 (2006.01) C07K 4/12 (2006.01) C07K 7/64 (2006.01) G01N 33/577 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2562133

The present invention is directed to novel antigens, antibodies and antigen binding fragments thereof, and to immunoassays and kits using these antigens and antibodies. The compositions and methods are useful in the determination of levels of cyclic analogs of human parathyroid hormone (hPTH) in sample fluids, such as serum or plasma. The antibodies and methods of the invention have the particular advantage of possessing binding specificity for cyclic analogs of human parathyroid hormone (hPTH).

L'invention concerne de nouveaux antigènes, anticorps et fragments de liaison aux antigènes, ainsi que des dosages immunologiques et des kits utilisant lesdits antigènes et anticorps. Les compositions et méthodes selon l'invention sont utiles pour déterminer des niveaux d'analogues cycliques de hPTH dans des fluides prélevés, tels que du sérum ou du plasma. Les anticorps et méthodes selon l'invention ont l'avantage de présenter une spécificité de liaison pour les analogues cycliques de hPTH.

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