Compositions and methods for detecting egfr mutations in cancer

Details Compositions and methods for detecting egfr mutations in cancer Compositions and methods for detecting egfr mutations in cancer

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 39/395 (2006.01) C07K 16/00 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2718975

The invention discloses binding agents to the E746 - A750 deletion and the L858R point mutations in the epidermal growth factor receptor (EGFR) molecule, and methods for use thereof, including methods for the diagnosis and treatment of cancer.

La présente invention concerne des agents de liaison à la délétion E746 - A750 et aux mutations ponctuelles L858R dans la molécule du récepteur de facteur de croissance épidermique (RFCE), ainsi que des procédés dutilisation de ces agents et notamment des procédés destinés au diagnostic et au traitement du cancer.

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