Compositions and methods for detecting ligand-dependent...

Details Compositions and methods for detecting ligand-dependent... Compositions and methods for detecting ligand-dependent...

G - Physics

01

N

G01N 33/53 (2006.01) C07K 2/00 (2006.01) C07K 4/00 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 16/00 (2006.01) C12N 15/10 (2006.01) G01N 33/50 (2006.01) G01N 33/542 (2006.01) G01N 33/567 (2006.01) G01N 33/58 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2326573

The invention provides a method based upon the two hybrid system for examining the interactions of nuclear receptors. The invention is additionally directed to compositions for use in the assay and a method of identifying ligands of nuclear receptors and their coactivator or corepressor proteins.

L'invention concerne une méthode, basée sur le système hybride double, destinée à identifier les interactions de récepteurs nucléaires. L'invention concerne, en outre, des compositions destinées à être utilisées dans l'analyse, et une méthode permettant d'identifier des ligands de récepteurs nucléaires ainsi que leurs protéines co-activateur et corépresseur.

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