Compositions and methods for detecting stress-inducible...

Details Compositions and methods for detecting stress-inducible... Compositions and methods for detecting stress-inducible...

C - Chemistry, Metallurgy

07

K

C07K 7/00 (2006.01) A61K 38/00 (2006.01) A61K 39/395 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2393589

Compositions and methods for detection of the stress-inducible Hsp70B' protein are disclosed. These include antibodies directed against particular amino acid regions of Hsp70B' and various peptides corresponding, or antigenically equivalent, to the regions. The ability to generate anti-Hsp70B' antibodies to defined epitopes permits a variety of in vitro and in vivo uses.

Compositions et procédés servant à détecter la protéine de stress Hsp70B'. Ces compositions et ces procédés consistent en des anticorps dirigés contre des zones aminoacides déterminées de Hsp70B' et différents peptides correspondant à ces zones ou équivalents à ces zones sur le plan antigénique. La capacité de génération d'anticorps anti-Hsp70B' par rapport à des déterminants antigéniques définis permet une variété de mises en application in vitro et in vivo.

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