Compositions and methods for determining the replication...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/70 (2006.01) C12N 15/09 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/569 (2006.01) G06T 1/00 (2006.01)

Patent

CA 2491392

This invention relates to compositions and methods for determining the replication capacity of a non-nucleoside reverse transcriptase inhibitor resistant virus. The compositions and methods are useful for identifying effective drug regimens for the treatment of viral infections, and identifying and determining the biological effectiveness of potential therapeutic compounds.

La présente invention concerne des compositions et des méthodes permettant de mesurer la capacité de réplication d'un virus résistant à un inhibiteur non nucléosidique de la transcriptase inverse. Ces compositions et ces méthodes sont utiles pour identifier des régimes posologiques efficaces destinés au traitement d'infections virales et pour identifier et mesurer l'efficacité biologique de composés thérapeutiques potentiels.

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