C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/26 (2006.01) A61K 31/557 (2006.01) A61K 45/00 (2006.01) A61P 3/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/573 (2006.01) G01N 33/68 (2006.01) G01N 33/88 (2006.01)
Patent
CA 2470431
The present invention provides compositions and methods for diagnosing and treating diabetes, insulin resistance and dyslipidemia. In particular, the invention provides methods of identifying modulators of AKR1C as well as methods of diagnosing diabetes by measuring the levels of AKR1C or 9.alpha., 11.beta.-PGF2.alpha. in a patient.
la présente invention concerne des compositions et des méthodes concernant le diagnostic et le traitement du diabète, de la résistance à l'insuline et de la dyslipidémie. Cette invention concerne en particulier des méthodes permettant d'identifier des modulateurs de AKR1C ainsi que des méthodes de diagnostic du diabète par mesure des niveaux de AKR1C ou de 9.alpha.,11.beta.-PGF¿2.alpha.? chez un patient.
Gustafson Thomas A.
Lavan Brian
Moodie Shonna
Waters Steve
Fetherstonhaugh & Co.
Metabolex Inc.
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