Compositions and methods for diagnosing and treating an...

C - Chemistry – Metallurgy – 07 – K

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C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01) C12N 15/13 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2621248

An isolated polypeptide is provided. The polypeptide comprising an antigen recognition domain capable of specifically binding a human scavenger receptor, wherein the antigen recognition domain comprises at least three CDR amino acid sequences selected from the group consisting of SEQ ID NO: 11, 15, 19, 23, 27 and 31. Also provided are compositions which comprise the peptide and uses of same.

L'invention concerne un polypeptide isolé. Ce polypeptide est composé d'un domaine de reconnaissance d'antigène capable de liaison spécifique avec un récepteur accepteur humain, ce domaine de reconnaissance d'antigène comprenant au moins trois séquences amino acide CDR (zone de détermination de complémentarité) sélectionnées dans le groupe constitué de SEQ ID NO: 11, 15, 19, 23, 27 et 31. Elle concerne également des compositions contenant ce peptide, ainsi que les utilisations de ce dernier.

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