C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/28 (2006.01) A61K 39/395 (2006.01) C07K 16/30 (2006.01) C07K 16/46 (2006.01) C12N 5/16 (2006.01) C12P 21/08 (2006.01) C07K 14/705 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2628221
An isolated antibody that specifically binds to an extracellular domain of two or more human FZD receptors and inhibits growth of tumor cells is described. Also described is a method of treating cancer comprising administering an antibody of the present disclosure in an amount effective to inhibit tumor cell growth.
La présente invention concerne un anticorps isolé qui se lie de manière spécifique à un domaine extracellulaire d'au moins deux récepteurs FZD humains et inhibe la croissance de cellules tumorales. Elle concerne également un procédé pour traiter un cancer, qui consiste à administrer un anticorps selon cette invention, dans une quantité efficace pour inhiber la croissance de cellules tumorales.
Gurney Austin
Hoey Timothy
Lewicki John
Satyal Sanjeev
Mbm Intellectual Property Law Llp
Oncomed Pharmaceuticals Inc.
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