Compositions and methods for diagnosing, predicting...

A - Human Necessities – 61 – K

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A61K 39/00 (2006.01)

Patent

CA 2605442

The present invention provides methods of diagnosing the presence of an autoimmune disease in a patient, methods of predicting the response of an autoimmune diseased patient to therapeutic treatment, and methods of monitoring an autoimmune patient's response to therapy. In particular, these methods comprise the use of a glycoprotein from the inner-ear organ of Corti reactive with a KHRI-3 monoclonal antibody.

La présente invention concerne des méthodes destinées à diagnostiquer la présence d'une maladie auto-immune chez un patient, des méthodes destinées à prédire la réponse d'un patient atteint d'une maladie auto-immune à un traitement, ainsi que des méthodes destinées à surveiller la réponse d'un patient atteint d'une maladie auto-immune à un traitement. Plus particulièrement, ces méthodes consistent à utiliser une glycoprotéine provenant de l'organe de Corti de l'oreille interne réactive à un anticorps monoclonal KHRI-3.

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