Compositions and methods for dosing liposomes of certain...

A - Human Necessities – 61 – K

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A61K 9/127 (2006.01) A61K 9/133 (2006.01)

Patent

CA 2480763

The present invention relates to pharmaceutical compositions comprising liposomes and methods of using such liposomes to prevent, treat, or manage a variety of diseases and/or bodily conditions. The liposomes may comprise large unilamellar vesicles (LUVs) alone or in combination with multilamellar vesicles (MLVs), small unilamellar vesicles (SUVs), or other therapeutics. The invention relates to liposomes having certain diameters administered to patients using specific doses and/or dosing regimens.

La présente invention concerne des compositions pharmaceutiques comprenant des liposomes, et des procédés d'utilisation de ces liposomes pour prévenir, traiter ou gérer diverses maladies et/ou affections corporelles. Les liposomes peuvent comprendre des gros liposomes unilamellaires (LUV) seuls ou combinés avec des liposomes multilamellaires (MLV), des petits liposomes unilamellaires (SUV), ou d'autres agents thérapeutiques. Cette invention concerne également des liposomes présentant certains diamètres, lesquels liposomes sont administrés à des patients par l'intermédiaire de doses spécifiques et/ou de schémas posologiques spécifiques.

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