Compositions and methods for effecting controlled posterior...

Details Compositions and methods for effecting controlled posterior... Compositions and methods for effecting controlled posterior...

A - Human Necessities

61

K

A61K 38/48 (2006.01) A61K 31/573 (2006.01) A61P 27/02 (2006.01)

Patent

CA 2643282

A composition comprises plasmin or an enzymatically equivalent derivative thereof and at least an anti-inflammatory medicament, such as triamcinolone acetonide. The composition can be used to effect or induce a controlled posterior vitreous detachment ("PVD") to prevent, treat, or ameliorate a potential complication of a pathological ocular condition. Such a composition can be administered intravitreally.

L'invention concerne une composition comprend de la plasmine ou un dérivé de celle-ci enzymatiquement équivalent, et au moins un médicament anti-inflammatoire. La composition peut être utilisée pour pratiquer ou induire un détachement vitreux postérieur (DVP) contrôlé afin de prévenir, de traiter, ou d'améliorer une complication potentielle d'une condition oculaire pathologique. Une telle composition peut être administrée intravitréennement.

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