Compositions and methods for eliciting an immune response to...

A - Human Necessities – 61 – K

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A61K 39/12 (2006.01) A61K 39/00 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2614884

Provided herein are cells, vectors and viruses in association with a mutant polypeptide that has emerged in response to a therapeutic or prophylactic agent; compositions comprising such cells, vectors and viruses and methods for their use in eliciting an immune response to the mutant polypeptide. In some examples, the immune response is a cellular immune response.

L'invention concerne des cellules, des vecteurs et des virus conjointement avec un polypeptide mutant ayant émergé en réponse à un agent thérapeutique ou prophylactique; des compositions comprenant de tels cellules, vecteurs et virus et des procédés d'utilisation de ceux-ci permettant d'éliciter une réponse immune au polypeptide mutant. Dans quelques exemples, la réponse immune est une réponse cellulaire immune.

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