A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 9/107 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/22 (2006.01) A61K 9/28 (2006.01) A61K 9/48 (2006.01)
Patent
CA 2380642
The present invention relates to pharmaceutical compositions, pharmaceutical systems, and methods for enhanced absorption of hydrophilic therapeutic agents. Compositions and systems of the present invention include an absorption enhancing carrier, where the carrier is formed from a combination of at least two surfactants, at least one of which is hydrophilic. A hydrophilic therapeutic agent can be incorporated into the composition, or can be co-administered with the composition as part of a pharmaceutical system. The invention also provides methods of treatment with hydrophilic therapeutic agents using these compositions and systems.
La présente invention concerne des compositions pharmaceutiques, des systèmes pharmaceutiques et des méthodes améliorant l'absorption d'agents thérapeutiques hydrophiles. Les compositions et les systèmes de la présente invention comprennent un excipient stimulant l'absorption, l'excipient étant composé d'une combinaison d'au moins deux tensioactifs, dont au moins un est hydrophile. Un agent thérapeutique hydrophile peut être ajouté à la composition ou il peut être coadministré avec la composition en tant que partie d'un système pharmaceutique. L'invention concerne également des méthodes de traitement avec des agents thérapeutiques hydrophiles utilisant ces compositions et systèmes.
Chen Feng-Jing
Patel Mahesh V.
Battison Williams Dupuis
Lipocine Inc.
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