A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 38/19 (2006.01) A61K 38/20 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2322699
The present invention provides compositions and methods for enhancing site- specific in vivo delivery of tumor associated antigens. Thus, in one aspect, this invention provides a method of recruiting antigen presenting cells (APCs) to a predetermined site in a subject. Methods of augmenting transduction of a transgene in vivo are also provided by this invention.
La présente invention concerne des compositions et des méthodes permettant d'améliorer l'apport ciblé in vivo d'antigènes associés aux tumeurs. Dans un aspect de cette invention, une méthode permet donc de mobiliser des cellules présentatrices de l'antigène (cellules APC) vers un site prédéterminé chez un sujet. L'invention concerne enfin des méthodes destinées à favoriser la transduction d'un transgène in vivo.
Perricone Michael A.
Roberts Bruce L.
Genzyme Corporation
Gowling Lafleur Henderson Llp
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