Compositions and methods for enhancement of major...

Details Compositions and methods for enhancement of major... Compositions and methods for enhancement of major...

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2353816

Compositions and methods for eliciting an in vivo cytotoxic lymphocyte (CTL) response against a modified soluble protein antigen are disclosed. The modified soluble protein antigen comprises an added peptidic sequence which facilitates entry of the modified antigen into antigen presenting cells (APC).

La présente invention concerne des compositions et des procédés permettant de susciter in vivo une réponse de cellules T cytotoxiques (CTL) dirigée contre un antigène protidique soluble modifié. Cet antigène protidique soluble modifié comprend une séquence peptidique supplémentaire qui facilite l'entrée de l'antigène modifié dans les cellules présentatrices de l'antigène (CPA).

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