Compositions and methods for enhancing accretion in skeletal...

A - Human Necessities – 61 – K

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A61K 31/198 (2006.01) A23L 1/30 (2006.01) A61K 31/121 (2006.01) A61K 31/385 (2006.01) A61K 31/661 (2006.01) A61P 21/06 (2006.01)

Patent

CA 2613119

A nutritional composition comprising at least an effective amount of geranylgeranylacetone or derivative of geranygeranylacetone and an effective amount of glutamine or derivative of glutamine, wherein the ingredients act substantially simultaneously to increase protein synthesis and inhibit protein degradation in skeletal muscle, via enhanced expression of heat shock proteins in cells, particularly heat shock protein 72. A method of same is also provided.

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