Compositions and methods for enhancing corticosteriod delivery

Details Compositions and methods for enhancing corticosteriod delivery Compositions and methods for enhancing corticosteriod delivery

A - Human Necessities

61

K

A61K 31/56 (2006.01) A61K 31/58 (2006.01) A61K 47/00 (2006.01) A61K 47/10 (2006.01) A61K 47/14 (2006.01) A61K 47/26 (2006.01) A61K 47/20 (2006.01) A61K 47/32 (2006.01)

Patent

CA 2471041

The present invention comprises a composition, method of enhancing potency and method of delivering corticosteroids in a vehicle comprising at least two penetration enhancers, and solvents and emulsifiers. The propylene glycol and penetration enhancers are present in ratio to the total of the propylene glycol, penetration enhancers, and solvents and emulsifiers of at least about 0.70.

L'invention concerne une composition, un procédé permettant de renforcer l'activité thérapeutique de cette composition et un procédé d'administration de corticostéroïdes dans un excipient comprenant au moins deux renforçateurs de pénétration, des solvants et des émulsifiants. Le propylèneglycol et les renforçateurs de pénétration sont présents selon un rapport au moins approximativement égal à 0,70, par rapport à la quantité totale de propylèneglycol, renforçateurs de pénétration, solvants et émulsifiants.

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