A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4706 (2006.01) A61K 31/423 (2006.01) A61K 31/4375 (2006.01) A61K 31/47 (2006.01) A61K 45/00 (2006.01) A61P 31/04 (2006.01) C12Q 1/18 (2006.01) C12Q 1/68 (2006.01) C40B 30/06 (2006.01)
Patent
CA 2603179
The present invention provides compositions useful in treating drug-resistant microorganisms and cells, as well as related methods of identifying and using such compositions. In addition, the present invention includes compositions useful in enhancing the sensitivity of both drug-resistant and drug-sensitive microorganisms and cells to microbicidal and cytotoxic agents, including antibiotics and chemotherapeutic drugs. Methods of identifying these compositions, as well as methods of using these agents in treating both drug- resistant and drug-sensitive diseases and conditions are further provided.
L'invention porte sur des compositions s'avérant utiles pour traiter les micro-organismes et les cellules présentant une résistance aux médicaments, et sur les méthodes associées d'identification et d'utilisation de telles compositions. L'invention porte également sur des compositions s'avérant utiles pour accroître la sensibilité de micro-organismes et de cellules à la fois résistant et sensibles aux médicaments et à des agents microbicides et cytotoxiques dont des antibiotiques et des produits chimiothérapeutiques. L'invention porte en outre sur des méthodes d'identification desdites compositions et des méthodes d'utilisation de ces agents pour traiter les maladies et états à la fois résistant et sensibles aux médicaments.
Cirz Ryan
Patten Philip A.
Romesberg Floyd
Achaogen Inc.
Fetherstonhaugh & Co.
The Scripps Research Institute
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