Compositions and methods for enhancing intestinal function

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/30 (2006.01) A61K 38/26 (2006.01) A61K 38/27 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2274596

GLP-2 stimulates the growth of both small intestine and large intestine tissue when administered in conjunction with other agents. The invention provides pharmaceutical compositions of GLP-2 with at least one other agent that increase the biological activity of GLP-2, methods of enhancing the growth of both small and large intestine tissue and of ameliorating nutritional or gastrointestinal disorders by increasing serum levels of GLP-2 and at least one other agent, and kits for performing the methods of the invention.

GLP-2 stimule la croissance à la fois du tissu de l'intestin grêle et du tissu du gros intestin quand on l'administre en combinaison avec d'autres agents. L'invention concerne des compositions pharmaceutiques de GLP-2 contenant au moins un autre agent amplifiant l'activité biologique de GLP-2, des procédés servant à améliorer la croissance des tissus de l'intestin grêle et du gros intestin, ainsi que les états provoqués par des maladies gastro-intestinales ou nutritionnelles, en augmentant les niveaux sériques de GLP-2 et d'au moins un autre agent, et des trousses servant à mettre ces procédés en application.

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