Compositions and methods for enzymatic treatment of lung...

Details Compositions and methods for enzymatic treatment of lung... Compositions and methods for enzymatic treatment of lung...

A - Human Necessities

61

K

A61K 38/44 (2006.01) A61K 31/573 (2006.01) A61K 31/7008 (2006.01) A61K 38/40 (2006.01) A61P 11/00 (2006.01) A61P 31/04 (2006.01) A61K 9/72 (2006.01) C12N 9/02 (2006.01) C12N 9/08 (2006.01)

Patent

CA 2687128

A therapeutic composition for the treatment of lung diseases or disorders and diseases or disorders of the airway passages including pneumonia, acute respiratory failure, and acute respiratory distress syndrome is based on the generation of a biocidal anion by an enzymatic reaction catalyzed by a peroxidase. The peroxide utilized by the peroxidase enzyme can be endogenous or can be generated by the action of an oxidase enzyme on a suitable substrate.

La présente invention concerne une composition thérapeutique destinée au traitement des maladies ou affections pulmonaires ou des maladies ou affections des voies aériennes, dont la pneumonie, l'insuffisance respiratoire aiguë et le syndrome de détresse respiratoire aiguë, ladite composition thérapeutique étant basée sur la génération d'un anion biocide par une réaction enzymatique catalysée par une peroxydase. Le peroxyde utilisé par l'enzyme peroxydase peut être endogène ou il peut être généré par l'action d'une enzyme oxydase sur un substrat approprié.

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