C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/87 (2006.01) A01K 67/00 (2006.01) A01K 67/027 (2006.01) C12N 5/10 (2006.01) C12N 15/00 (2006.01) C12N 15/88 (2006.01)
Patent
CA 2651423
The present invention provides methods of altering gene expression of embryos to provide compositions and methods for efficient generation of transgenic animals. In particular, the present invention provides compositions and methods for generating germ-line transgenic animals by direct injection of nucleic acid molecules into animals.
La présente invention concerne des méthodes pour changer l'expression d'un gène d'embryons dans le but d'obtenir des compositions, et des méthodes pour une production efficace d'animaux transgéniques. En particulier, la présente invention fournit des compositions et des méthodes pour générer des animaux transgéniques de lignée germinale par injection directe de molécules d'acide nucléique dans lesdits animaux.
Deboer Lisa
Gratsch Theresa
O'shea Sue
Velkey Matt
Welsh Michael J.
Smart & Biggar
The Regents Of The University Of Michigan
LandOfFree
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