Compositions and methods for improved cell culture

Details Compositions and methods for improved cell culture Compositions and methods for improved cell culture

C - Chemistry, Metallurgy

12

N

C12N 5/071 (2010.01) C12N 5/10 (2006.01) C12N 9/12 (2006.01) C12N 15/54 (2006.01) C12P 21/02 (2006.01) C07K 14/475 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2383073

The invention provides improved methods of recombinant protein production in cell culture. More specifically, the invention relates to the modulation of the IGF-1 signaling pathway in cells so as to improve production characteristics.

L'invention concerne des procédés améliorés permettant de produire des protéines recombinantes en culture cellulaire. L'invention porte plus particulièrement la modulation des voies de signalisation de l'IGF-1 dans les cellules permettant d'améliorer les caractéristiques de production.

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