Compositions and methods for increasing insulin sensitivity

Details Compositions and methods for increasing insulin sensitivity Compositions and methods for increasing insulin sensitivity

A - Human Necessities

61

K

A61K 31/00 (2006.01) A61K 31/135 (2006.01) A61K 31/138 (2006.01) A61K 31/423 (2006.01) A61K 31/4525 (2006.01) A61K 31/485 (2006.01) A61K 31/55 (2006.01) A61K 31/551 (2006.01) A61K 31/7048 (2006.01) A61K 45/06 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2630624

Methods and compositions for treating a blood glucose condition involve identifying a suitable subject and administering an effective amount of a composition that contains one or more of an opioid antagonist, an anticonvulsant, and a psychotherapeutic agent. The compositions can include insulin. In some embodiments, such methods and compositions can be used to modulate a blood glucose level. In preferred embodiments, such methods and compositions are useful for increasing a subject's sensitivity to insulin.

La présente invention concerne des procédés et des compositions de traitement d~une condition de glucose dans le sang qui impliquent l~identification d~un sujet adéquat et l~administration d~une quantité effective d~une composition qui contient au moins un antagoniste opioïde, un anticonvulsif et un agent psychothérapeutique. Ces compositions pourront contenir de l~insuline. Dans certains modes de réalisation, de tels procédés et compositions peuvent s~utiliser pour moduler un niveau de glucose dans le sang. Dans les modes de réalisation préférés, de tels procédés et compositions sont utiles pour augmenter la sensibilité d~un patient à l~insuline.

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