Compositions and methods for induction of antigen-specific...

A - Human Necessities – 61 – K

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A61K 39/385 (2006.01) A61P 37/06 (2006.01)

Patent

CA 2750098

The present invention utilizes carrier particles to present antigen peptides and proteins to the immune system in such a way as to induce antigen specific tolerance. The carrier particle is designed in order to trigger an immune tolerance effect. The invention is useful for treatment of immune related disorders such as autoimmune disease, transplant rejection and allergic re-actions.

La présente invention utilise des particules porteuses pour présenter des peptides antigènes et des protéines antigènes au système immunitaire de façon à induire une tolérance spécifique aux antigènes. Les particules porteuses sont conçues afin de déclencher un effet de tolérance immunitaire. L'invention est utile pour le traitement de troubles immunitaires tels qu'une maladie auto-immune, un rejet de transplantation et des réactions allergiques.

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