C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) G06F 19/18 (2011.01)
Patent
CA 2496155
Ancestry informative marker (AIMs) polynucleotides that contain a single nucleotide polymorphism or that contain an insertion or deletion, are provided, as are methods of using panels of the AIMs to draw an inference as to a trait of an individual. The trait can be, for example, biogeographical ancestry, a pigmentation trait, responsiveness to a drug, or susceptibility to a disease. Also provided are methods of determining the proportional ancestry of an individual. Reagents and kits also are provided.
L'invention concerne des polynucléotides de marqueurs d'informations d'ascendance (AIM) qui contiennent un seul polymorphisme nucléotidique ou une insertion ou une suppression, ainsi que des méthodes d'utilisation de panneaux d'AIM permettant de déduire une inférence comme trait d'un individu. Ce trait peut être, for exemple, un ancêtre biogéographique, un trait de pigmentation, une réactivité à un médicament, ou une susceptibilité à une maladie. L'invention concerne également des méthodes permettant de déterminer la proportion d'ascendance d'un individu. L'invention concerne enfin des réactifs et des kits.
Frudakis Tony N.
Shriver Mark D.
Dnaprint Genomics Inc.
Osler Hoskin & Harcourt Llp
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