Compositions and methods for inhibiting angiogenesis

Details Compositions and methods for inhibiting angiogenesis Compositions and methods for inhibiting angiogenesis

A - Human Necessities

61

K

A61K 38/55 (2006.01) A61K 38/57 (2006.01) A61K 48/00 (2006.01) A61P 9/00 (2006.01) A61P 17/06 (2006.01) A61P 27/00 (2006.01) A61P 35/00 (2006.01) C12Q 1/02 (2006.01) G01N 33/50 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2344613

The invention provides for methods of reducing or inhibiting angiogenesis, tumor growth and endothelial cell proliferation by the administration of compositions containing fragments, conformations, biological equivalent, or derivatives of antithrombin III. The invention also provides for pharmaceutical compositions comprising a fragment, conformation, biological equivalent, or derivative of antithrombin III and methods of identifying novel inhibitors of tumor growth, endothelial cell proliferation, and/or angiogenesis. The invention also relates to compositions and methods for altering angiogenesis in a mammal, as well as to methods of treatment for disorders associated with angiogenesis (e.g., cancer).

L'invention se rapporte à des méthodes permettant de réduire ou d'inhiber l'angiogenèse, la croissance tumorale et la prolifération cellulaire endothéliale. Ces méthodes consistent à administrer des compositions comportant des fragments, des conformations, des équivalents biologiques ou des dérivés d'antithrombine III. L'invention se rapporte également à des compositions pharmaceutiques comportant un fragment, une conformation, un équivalent biologique ou un dérivé d'antithrombine III ainsi qu'à des méthodes d'identification de nouveaux inhibiteurs de croissance tumorale, de prolifération cellulaire endothéliale et/ou d'angiogenèse. L'invention se rapporte en outre à des compositions et à des méthodes permettant de modifier l'angiogenèse chez un mammifère, ainsi qu'à des méthodes de traitement des troubles associés à l'angiogenèse (par exemple, le cancer).

Affiliated with

Also associated with

Rating

Compositions and methods for inhibiting angiogenesis does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions and methods for inhibiting angiogenesis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods for inhibiting angiogenesis will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2067884